The Petroleum HPV Testing Group has volunteered to sponsor 389 high production volume chemical substances in EPA's HPV Challenge" program. The number of laboratory animals used will be minimized to the greatest extent possible within the constraints of the program’s requirements, and studies will be conducted according to EPA/OECD guidelines. In addition, only laboratories accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) for excellence in animal care will be used.

To meet these objectives, the Testing Group has designed a program which maximizes the use of existing health and environmental data while significantly reducing the overall number of tests needed. The similarity of many petroleum substances allows for their grouping into categories based on physical-chemical properties and use in finished products. Petroleum substances representative of each category will be used as test materials to develop health and environmental effects information which can be extrapolated to all the substances in their category. .

For more information on chemical testing and animal welfare under the HPV program visit EPA and the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International).

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